OPA1 Deletion in the Heart Induces Altered Mitochondrial Morphology and Dilated Cardiomyopathy
Heart Failure (HF) is a global pandemic affecting 26 million people worldwide. Altered mitochondrial dynamics may contribute to the pathogenesis of heart failure.
Leveraging TriNetX to Discover CVD Phenotypes in Rare Diseases
Elucidating cardiovascular comorbidities in patients with genetic diseases including Autosomal Dominant Optic Atrophy, Cystic Fibrosis, and Chronic Granulomatous Disease.
Radiopaque Aptamer Dimers as Next-Generation Contrast Agents
Using aptamer technology to identify RNA aptamers that bind to cardiovascular tissues that can be utilized in cardiovascular diagnostics and therapeutics.
Using Spatial Transcriptomics to Identify Key Regulators of Plaque Regression
Applying Visium spatial sequencing to identify unique transcriptome signatures associated with the regression of atherosclerotic plaques in humans and mice.